ELECTRIC FIELD STIMULATION DIRECTS TARGET-SPECIFIC AXON REGENERATION AND PARTIAL RESTORATION OF VISION AFTER OPTIC NERVE CRUSH INJURY.

Failure of central nervous system (CNS) axons to regenerate after injury results in permanent disability.Several molecular neuro-protective and neuro-regenerative strategies have been proposed as potential treatments but do not provide the directional cues needed to direct target-specific axon regeneration.Here, we demonstrate that applying an exte

Immunoglobulin light chain (AL) amyloidosis is a rare plasma cell dyscrasia characterized by the deposition of abnormal amyloid fibrils in multiple organs, thus impairing their function.In the largest cohort studied up to now of 118 CD138-purified plasma cell samples from previously untreated immunoglobulin light chain amyloidosis patients, we asse